‹ Distribution Symmetry ›

Links between groups


The heatmap shows the estimates for pairwise comorbidity. These estimates were computed using cox proportional hazards model with adjustment for i) country, age-cohort and sex (Model A) ii) adjusted for country, age-cohort, sex, type and number of mental disorders with onset preceding the prior disorder (Model B)

Sex: Model:

We found that associations are particularly strong for the following pairs (yellow in the heatmap):

  • Bulimia and binge eating disorder (HR: 110, 95% CI= 98.4-124.8)
  • Drug abuse and drug dependence (HR: 66, 95% CI = 57.9-75.1)
  • MDE and dysthymia (HR: 60.5, 95% CI = 55.1-66.4)

There were moderate evidence of associations for the following pairs (purple in the heatmap):

  • Nicotine dependence and OCD (HR: 5.3, 95% CI = 4-6.9)
  • Nicotine dependence and Bulimia nervosa (HR: 5.6, 95% CI = 4.1-7.7)
  • Alcohol dependence and OCD (HR: 5.3, 95% CI = 4.4-6.4)